BRCA1 p.S114T Reference Standard
CBP10356
詢 價(jià)
索取COA
產(chǎn)品描述
產(chǎn)品數(shù)據(jù)庫(kù)
| Introduction | |
| Format | Genomic DNA |
| Description | BRCA1, BRCA1 DNA repair associated, is a tumor suppressor (PMID: 30562755) involved in the DNA damage response and DNA repair (PMID: 21203981). BRCA1 germline mutations increase the risk of developing ovarian and/or breast cancer (PMID: 21285145) and somatic mutations are highest in NSCLC, pancreatic, and colon cancers (PMID: 27283171). |
| Technical Data | |
| DNA Change | c.340T>A |
| AA Change | p.S114T |
| Mutation type | Missense_Mutation |
| Zygosity | Heterozygous |
| Allelic Frequency | 66.67% |
| Cosmic ID | COSM13842 |
| Chr position(GRCh37) | chr17:41256240 |
| Transcript | ENST00000357654 |
| Buffer | Tris-EDTA |
| Product Information | |
| Intended Use | Research Use Only |
| Unit Size | 1ug |
| Concentration | Download for COA |
| Purofication | Download for COA |
| DNA electrophoresis | Download for COA |
| Sanger sequencing |  |
| Storage | 2-8°C |
| Expiry | 36 months from the date of manufacture |
