RB1 p.E204Kfs*10 Reference Standard
CBP10451
詢 價
索取COA
產(chǎn)品描述
產(chǎn)品數(shù)據(jù)庫
| Introduction | |
| Gene | RB1 |
| Description | RB1, retinoblastoma-associated protein, is a key negative regulator of the G1 to S transition during cell division (PMID: 15084261) and also plays a role in cell differentiation, survival, senescence, epigenetic regulation, and genome stability (PMID: 21295686, PMID: 23359405, PMID: 22293180). Inactivation of Rb1 and loss of Rb1 tumor suppressor function has been identified in many early stage cancers (PMID: 26160835). |
| Technical Data | |
| DNA Change | c.610delG |
| AA Change | p.E204Kfs*10 |
| Mutation type | Splice_Site |
| Zygosity | Homozygous |
| Allelic Frequency | 100.00% |
| Transcript | ENST00000267163.4 |
| Cosmic ID | N/A |
| Chr position(GRCh37) | chr13:48934155 |
| Buffer | Tris-EDTA |
| Product Information | |
| Intended Use | Research Use Only |
| Unit Size | 1ug |
| Concentration | Download for COA |
| Purofication | Download for COA |
| DNA electrophoresis | Download for COA |
| Sanger sequencing |  |
| Storage | 2-8℃ |
| Expiry | 36 months from the date of manufacture |
