AI-Edigene? BCR-ABL1(E14-E2) Fusion
CBP20226R
詢 價(jià)
索取COA
產(chǎn)品描述
產(chǎn)品數(shù)據(jù)庫(kù)
| Introduction | |
| Format | RNA |
| Description | Presence of a BCR-ABL1 fusion gene is necessary for the pathogenesis of CML. In up to 95% of cases, a t(9;22) (q34;q11) translocation results in the BCR-ABL1 fusion gene (Faderl et al. 1999). This translocation results in the Philadephia chromosome. In rare CML cases lacking the traditional t(9;22) translocation, other translocations result in the creation of the BCR-ABL1 fusion gene, which sometimes involve multiple chromosomes. |
| Technical Data | |
| Left Gene | BCR(E14) |
| Left Breakpoint | hg19 chr22:23632600:+ |
| Right Gene | ABL1(E2) |
| Right Breakpoint | hg19 chr9:133729451:+ |
| Buffer | RNase-free H2O |
| Product Information | |
| Intended Use | Research Use Only |
| Unit Size | 1ug |
| Concentration | Download for COA |
| Purity | Download for COA |
| RNA electrophoresis | Download for COA |
| Sanger sequencing |  |
| Storage | -90~ -70℃ |
| Expiry | 12 months from the date of manufacture |
