Lentiviral Vector Integration Site Reference Standard
CBPL0002
產(chǎn)品描述
產(chǎn)品數(shù)據(jù)庫
| Introduction | |||
| Cat No. | CBPL0002 | ||
| Format | Genomic DNA | ||
| Description | 該產(chǎn)品可用于基因編輯細(xì)胞治療法方法（包括CART治療）的安全性評估。該產(chǎn)品經(jīng)NGS(捕獲法)和Sanger測序法雙重驗(yàn)證，表明適合作為LV整合位點(diǎn)分析的定性參考試劑。該產(chǎn)品能夠可靠的檢測到以下6個位點(diǎn)，整合頻率為50%。 | ||
| LV Integration sites(hg19) | |||
| Chromosome | Start（approx） | Gene | 整合頻率 |
| 3 | 4871944 | ITPR1 | 50% |
| 4 | 288630 | ZNF732 | 50% |
| 9 | 130845722 | SLC25A25 | 50% |
| 9 | 33997906 | UBAP2 | 50% |
| 17 | 18494286 | CCDC144B | 50% |
| 22 | 50808061 | PPP6R2 | 50% |
| Representative Data | |||
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| Figure 1. Sanger sequencing result of ITPR1. | |||
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| Figure 2. Sanger sequencing result of ZNF732. | |||
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| Figure 3. Sanger sequencing result of SLC25A25. | |||
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| Figure 4. Sanger sequencing result of UBAP2. | |||
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| Figure 5. Sanger sequencing result of CCDC144BP. | |||
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| Figure 6. Sanger sequencing result of PPP6R2. | |||
| Product Information | |||
| Intended Use | Research Use Only | ||
| Unit Size | 1ug | ||
| Concentration | Download for COA | ||
| Purity | Download for COA | ||
| DNA electrophoresis | Download for COA | ||
| Storage | 2-8°C | ||
| Expiry | 36 months from the date of manufacture | ||
